Sirolimus-Eluting Balloons (SEB) for ISR
For years, the standard treatment for In-Stent Restenosis (ISR)—where a stent itself becomes blocked—was to place another stent inside the first one. In 2026, the SELUTION DeNovo and SELUTION4ISR trials have proven that Sirolimus-Eluting Balloons (SEB) are just as effective as repeat stenting.
By using a balloon to deliver the drug directly to the blockage and then removing the device, surgeons can treat the narrowing without adding more metal layers ("onion skinning"). This is now the 2026 "Gold Standard" for complex repeat procedures, as it keeps the vessel flexible and preserves options for future bypass surgery if it ever becomes necessary.
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